What is rheumatic heart disease?
Rheumatic heart disease is a condition in which the heart
valves are damaged by rheumatic fever. Rheumatic fever begins
with a strep throat from streptococcal infection.
Rheumatic fever is an inflammatory disease. It can affect
many of the bodys connective tissues especially
those of the heart, joints, brain or skin. When rheumatic
fever permanently damages the heart, the damage is called
rheumatic heart disease.
Anyone can get acute rheumatic fever, but it usually occurs
in children 5 to 15 years old. The rheumatic heart disease
that results can last for life.
How can you tell if you have strep throat?
The most common symptoms of strep throat are the sudden
onset of a sore throat (particularly with painful swallowing),
fever, and tender, swollen glands under the jaw angle.
Laboratory tests can confirm inflammation and identify a streptococcal
infection. Theres no specific lab test for rheumatic
fever. Strep throat infections can be detected by throat cultures
or more rapid laboratory antigen detection tests.
Throat cultures, blood antibody tests and other blood tests
are also used to find out if a recent strep infection could
have triggered rheumatic fever.

What happens in acute rheumatic fever?
The first symptoms are a high fever that lasts 10 to 14
days and arthritic pain and soreness that moves from one joint
to another. In acute attacks of rheumatic fever, joints often
swell and become red and hot.
A child suffering from rheumatic fever may have shortness
of breath or chest pains. These symptoms indicate the heart
is affected. Other signs include tiring easily, eating poorly
or paleness. A doctor examining the child may hear an abnormal
heart murmur or find that the heart is enlarged. Acute inflammation
of the heart is a serious condition. It requires direct and
some-times lengthy medical care.

What tests are used to detect heart damage?
Chest X-rays and an electrocardiogram are two common tests
to find out if the heart has been affected.
Echocardiography sends sound waves into the chest to rebound
from the hearts walls and valves. The recorded waves
show the shape, texture and movement of the valves. They also
show the size of the heart chambers and how well theyre
working. This technique doesnt hurt or pose a risk to
people.
Doctors also use cardiac catheterization to study heart damage.

What happens when rheumatic heart disease
damages a heart valve?
A damaged heart valve either doesnt fully close
(insufficiency) or doesnt fully open (stenosis).
A heart valve that doesnt close properly lets blood
leak back into the chamber from which it was pumped. This
is called regurgitation or leakage. With the next heartbeat,
regurgitated blood flows through the valve and mixes with
blood that flows normally. This extra volume of blood puts
more strain on the heart muscle. A doctor can diagnose an
insufficient heart valve by listening to the heart and verify
it by echocardiography.
When a valve doesnt open enough, the heart must pump
harder than normal to force
blood through the narrowed opening. Usually there are no symptoms
until the valve opening becomes very narrow. With modern diagnostic
tools, however, doctors can discover valves that cant
open fully many years before people complain of discomfort.

What are the symptoms of rheumatic heart
disease?
Symptoms vary greatly. Often the damage to heart valves
isnt immediately noticeable. Some people have no problem
or feel only mild discomfort for years.
Eventually, damaged heart valves can cause serious, even disabling,
problems. These
problems depend on how bad the damage is and which heart valve
is affected. Valve abnormalities on the hearts left
side (the mitral and aortic valves) usually cause symptoms
earlier than abnormalities on the right side. The reason is
that blood pressures are higher on the hearts left side.
(The tricuspid valve is usually the only valve affected by
rheumatic heart disease on the right side of the heart. The
pulmonic valve is almost never affected.)
People with mitral or aortic valves that dont fully
close find that their heart becomes overactive during vigorous
work or play, or during emotional excitement. Increased physical
or emotional activity puts more strain on a heart thats
already overworked because of the leaking valve.
As a result, the left ventricle gradually gets bigger to make
up for the added volume of
blood. Eventually this becomes counterproductive, and the
heart cant pump enough blood. Pressure builds in the
ventricle and causes blood to back up into the lungs, causing
shortness of breath. It can result in an inadequate blood
supply to the body and fatigue. The body also may retain fluid.
The lungs of people with mitral valve stenosis are under more
pressure. This puts an extra burden on the hearts right
side, since it must pump against the raised pressure. The
added pressure in the lungs also causes fluid retention (pulmonary
edema) and shortness of breath.
In aortic valve stenosis, the extra pressure and larger size
of the left ventricle means the heart muscle itself needs
more blood. If the coronary arteries dont supply enough
blood to the heart tissue, angina pectoris can occur. Dizziness
or fainting during exertion, shortness of breath, fatigue
and palpitations are other symptoms of the same problem. The
most advanced condition is congestive heart failure.

How can rheumatic heart disease be prevented?
The best defense against rheumatic heart disease is to
prevent rheumatic fever from ever occurring. By treating strep
throat with penicillin or other antibiotics, doctors can usually
stop acute rheumatic fever from developing.
Often
a doctor will wait for the result of a throat culture to be
sure a strep infection is present and antibiotics are warranted.
Most sore throats are caused by viral infections that arent
helped by antibiotic treatment. Strep throats are bacterial
infections, so antibiotics help them. People whove had
rheumatic fever are at risk for more attacks and heart damage.
Thats why theyre given continuous monthly or daily
antibiotic treatment, maybe for life. If their heart has been
damaged by rheumatic fever, theyre also given a different
antibiotic when they undergo dental or surgical procedures.
This helps prevent bacterial endocarditis, a dangerous infection
of the hearts lining or valves.
What can be done about a bad heart valve?
When heart valves are damaged by rheumatic fever, they
may not open or close properly. If they dont open properly,
they block the forward flow of blood. If they dont close
properly, blood may leak backwards.
When these problems occur, valve replacement surgery may be
recommended. In this surgery the diseased valve is replaced
with a metal or plastic valve, or with a specially prepared
valve from another human heart (cadaver valve) or from an
animal such as a pig (porcine valve). Most people who have
valve replacement surgery improve markedly.
